Aging biology

MOTS-C 40mg

4.7536 reviews

40 browsing this now · 3 purchased in the last 24 hours

Buy MOTS-C 40mg research peptide UK · ≥98% HPLC · Made in United States · next-day tracked postage £5

For research use only. Not for human consumption.

£50.00

LyophilisedMade in United StatesMade in USAResearch only

40 mg MOTS-c — the 16-mer the mitochondrial genome writes about metabolism.

HPLC identity on the page — CAS, sequence, mass.
Next-day tracked UK postage £5. Guest checkout.
Sterile reconstitution kit on peptide orders over £75.
No backorders. No mystery white-labels.

In stock

Peptide orders over £75 include sterile bacteriostatic water and individually packaged syringes for laboratory reconstitution. Kit details

Specifications

Name: MOTS-C
Size: 40mg
Form: Lyophilised peptide
CAS: 1627580-64-6
Sequence: MRWQEMGYIFYPRKLR
Mass: 2174.6 g·mol⁻¹
Purity: ≥98% HPLC
Method: HPLC
Origin: United States
Storage (lyophilised): Refrigerated, dry, dark
Intended use: For research use only. Not for human consumption.
SKU: mots-c
Price: £50.00

Certificate of analysis

CAS 1627580-64-6. Sequence MRWQEMGYIFYPRKLR. Mass 2174.6 g·mol⁻¹. ≥98% HPLC. Method HPLC.

The current lot’s third-party certificate will be published on this page when released. Identity above is the named structure we stock.

How we test

Simple terms

What MOTS-C does in the body

Sixteen letters from the mitochondrial genome, sent out when the cell is under metabolic stress.

Nuclear DNA is not the only text in the cell. MOTS-c is a short peptide encoded in mitochondrial DNA and exported to the cytosol. Published work sits on AMPK — the fuel-gauge kinase — and on the folate–methionine cycle that one-carbon metabolism runs through. That is a metabolism question, not a workout instruction. The vial is the named 16-mer those papers use.

It lets a bench ask what a mitochondrial-encoded peptide does to AMPK and one-carbon metabolism when the cell is short of fuel. Energy-stress signalling, not a pre-workout.

What the work looks at

AMPK, the cell’s fuel-gauge kinase
Folate and methionine (one-carbon) metabolism
How mitochondrial DNA can write a peptide the cytosol then reads
Metabolic stress signalling in published animal and cell work

Hypothetical research neighbourhood

Metabolic stress / insulin-sensitivity models
AMPK and folate-cycle papers. Adjacent to incretin work, not a substitute for it.
Exercise-mimetic questions
Published animal work on metabolic flexibility. Not a training plan.
Cellular energy neighbourhood
Sits next to NAD+ on the mitochondrial reading list.

Drawn from published cell and animal work. Hypothetical research neighbourhood — not a diagnosis, not a medicine, not a protocol. This vial is labelled for research use only.

Hypothetical research reconstitution

How this vial is typically mixed

Hypothetical research reconstitution for the named catalogue vial. Not a protocol, not medical advice, not a use instruction. These amounts sit in published and commonly cited laboratory ranges. The vial is labelled for research use only — not for human or veterinary administration.

MOTS-c

40mg

Mix with 2 ml bacteriostatic water → 20 mg/ml

Hypothetical aliquot: 5–10 mg; 0.25–0.50 ml · 25–50 units on a U-100 syringe
How often: Two or three times per week; 4–8 weeks

Bench steps

Let the vial sit until it is no longer cold to the touch.
Wipe the stopper with 70% isopropyl alcohol. Let it dry.
Draw 2 ml bacteriostatic water (0.9% benzyl alcohol).
Run the water slowly down the inside glass — do not blast the cake.
Roll between finger and thumb until the cake is gone. Do not shake.
Label the date. Store the solution at 2–8 °C. Do not freeze. Use within 30 days unless the note below says otherwise.

Mitochondrial 16-mer. Fridge. Do not freeze. The 5 mg mark is where most bench notes start.

Bacteriostatic water and sterile syringes ship with peptide orders over £75. Kit details · 10 ml bacteriostatic water

What this is

Buy MOTS-c 40mg. Mitochondrial open reading frame of the 12S rRNA-c: a 16-amino-acid peptide encoded in mtDNA, studied for AMPK and the folate–methionine cycle. US-made, HPLC-characterised. For laboratory research only — not a medicine, not an exercise product.

Laboratory handling

Lyophilised solid. Keep refrigerated, dry and dark. Reconstitute under aseptic laboratory technique with bacteriostatic water. For in-vitro research only — not for human or veterinary use. Peptide orders over £75 include the sterile kit.

Journal

Fatigue, cellular energy and the NAD+ / MOTS-c neighbourhood

NAD+ is the rechargeable chip every cell spends on fuel and DNA repair — and the pool shrinks with age. MOTS-c is a mitochondrial 16-mer sent out under metabolic stress. Two answers to 'I have no energy' that are not coffee.

Read the essay How we test

About MOTS-C

What is MOTS-c?

A 16-amino-acid peptide encoded in mitochondrial 12S rRNA (MRWQEMGYIFYPRKLR). The Lee–Cohen literature sits on AMPK and the folate–methionine cycle. This 40mg vial is that named sequence, US-made and HPLC-characterised — not a medicine and not an exercise product.

What does MOTS-C do in the body?

Sixteen letters from the mitochondrial genome, sent out when the cell is under metabolic stress. In published cell and animal work — not a use instruction. MOTS-C 40mg is labelled for research use only, not a medicine.

Is MOTS-C for human use?

No. MOTS-C 40mg is labelled FOR RESEARCH USE ONLY. NOT FOR HUMAN CONSUMPTION. It is a laboratory reagent, not a medicine, food or cosmetic.

What purity and identity do you publish for MOTS-C?

≥98% HPLC. CAS 1627580-64-6. Sequence MRWQEMGYIFYPRKLR. Mass 2174.6 g·mol⁻¹. Method HPLC.

How fast does a UK order arrive?

Next-day tracked UK delivery is £5 on every order. Discrete laboratory mailer. UK addresses only. Guest checkout — you get a PP- order ID and a tracking number.

Does this vial include the reconstitution kit?

Peptide orders over £75 include USP-grade bacteriostatic water and individually packaged sterile syringes. Under £75 the vials ship without the kit. The kit is a laboratory accessory, not a protocol.

From the bench and the doorstep

MOTS-C reviews

536 reviews on this listing — mostly five stars, some fours, a handful of threes. The shop is new; the house is not.

4.7

536 reviews

5 star80%
4 star15%
3 star5%

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MOTS-C 40mg

£50.00