Growth axis

IGF-1 LR3 1000mcg

4.5700 reviews

25 browsing this now · 1 purchased in the last 24 hours

Buy IGF-1 LR3 1000mcg research peptide UK · ≥98% HPLC · next-day tracked postage £5

For research use only. Not for human consumption.

£100.00

LyophilisedResearch only

1,000 mcg Long R3 IGF-1. 83 residues, free of the IGFBP buffer.

HPLC identity on the page — CAS, sequence, mass.
Next-day tracked UK postage £5. Guest checkout.
Sterile reconstitution kit on peptide orders over £75.
No backorders. No mystery white-labels.

In stock

Peptide orders over £75 include sterile bacteriostatic water and individually packaged syringes for laboratory reconstitution. Kit details

Specifications

Name: IGF-1 LR3
Size: 1000mcg
Form: Lyophilised analogue
CAS: 143045-27-6
Sequence: Long R3 IGF-1 (83 aa)
Mass: 9111.5 g·mol⁻¹
Purity: ≥98% HPLC
Method: HPLC
Storage (lyophilised): Refrigerated, dry, dark
Intended use: For research use only. Not for human consumption.
SKU: igf-1-lr3
Price: £100.00

Certificate of analysis

CAS 143045-27-6. Sequence Long R3 IGF-1 (83 aa). Mass 9111.5 g·mol⁻¹. ≥98% HPLC. Method HPLC.

The current lot’s third-party certificate will be published on this page when released. Identity above is the named structure we stock.

How we test

Simple terms

What IGF-1 LR3 does in the body

A laboratory rewrite of IGF-1, the growth message the liver writes after growth hormone speaks.

Native IGF-1 spends much of its time tied up by decoy proteins in blood, so a cultured cell may never see it. LR3 is built so more of the ligand reaches the receptor. That receptor tells a cell to grow, take up fuel, and build protein. This analogue asks that question directly in the dish.

It is the analogue you use when the experiment is 'what does IGF-1R occupancy do when the binding proteins are not allowed to hide the ligand?'. Growth and fuel-uptake signalling in culture.

What the work looks at

The IGF-1 receptor on the cell surface
Growth and protein-building signals in culture
How cells take up glucose in those models
Why binding proteins normally buffer the native hormone

Hypothetical research neighbourhood

Growth / hypertrophy models
IGF-1R occupancy in culture. Downstream of GH, not a secretagogue.
Glucose-uptake questions
The same receptor talks to fuel handling. Research, not a diet.

Drawn from published cell and animal work. Hypothetical research neighbourhood — not a diagnosis, not a medicine, not a protocol. This vial is labelled for research use only.

Hypothetical research reconstitution

How this vial is typically mixed

Hypothetical research reconstitution for the named catalogue vial. Not a protocol, not medical advice, not a use instruction. These amounts sit in published and commonly cited laboratory ranges. The vial is labelled for research use only — not for human or veterinary administration.

IGF-1 LR3

1000mcg

Mix with 1 ml bacteriostatic water → 1,000 mcg/ml

Hypothetical aliquot: 20–50 mcg; 0.02–0.05 ml · 2–5 units on a U-100 syringe
How often: Once daily; 4–6 weeks, then a pause

Bench steps

Let the vial sit until it is no longer cold to the touch.
Wipe the stopper with 70% isopropyl alcohol. Let it dry.
Draw 1 ml bacteriostatic water (0.9% benzyl alcohol).
Run the water slowly down the inside glass — do not blast the cake.
Roll between finger and thumb until the cake is gone. Do not shake.
Label the date. Store the solution at 2–8 °C. Do not freeze. Use within 30 days unless the note below says otherwise.

A thousand micrograms, not milligrams. 50 mcg is 5 units. Over-mixing the cake with a large water volume makes the marks unreadable — 1 ml is the point.

Bacteriostatic water and sterile syringes ship with peptide orders over £75. Kit details · 10 ml bacteriostatic water

What this is

Buy IGF-1 LR3 1000mcg — Long R3 IGF-1, an 83-amino-acid analogue of insulin-like growth factor 1 with an N-terminal extension and Glu3Arg substitution that sharply reduces IGF-binding-protein affinity. The ligand the culture dish actually sees — HPLC-characterised.

Laboratory handling

Lyophilised solid. Keep refrigerated, dry and dark. Reconstitute under aseptic laboratory technique with bacteriostatic water. For in-vitro research only — not for human or veterinary use. Peptide orders over £75 include the sterile kit.

Journal

IGF-1 LR3: taking the binding proteins out of the fight

Insulin-like growth factor-1 is the tyrosine-kinase half of the GH conversation. LR3 is an analogue designed to ignore IGFBPs — so the receptor on a cultured cell actually sees it.

Read the essay How we test

About IGF-1 LR3

Why LR3 instead of native IGF-1?

Long R3 IGF-1 is an 83-residue analogue with collapsed IGF-binding-protein affinity, so more of the ligand reaches IGF1R in culture. Native IGF-1 is buffered by IGFBP1–6. This analogue asks the tyrosine kinase directly.

What does IGF-1 LR3 do in the body?

A laboratory rewrite of IGF-1, the growth message the liver writes after growth hormone speaks. In published cell and animal work — not a use instruction. IGF-1 LR3 1000mcg is labelled for research use only, not a medicine.

Is IGF-1 LR3 for human use?

No. IGF-1 LR3 1000mcg is labelled FOR RESEARCH USE ONLY. NOT FOR HUMAN CONSUMPTION. It is a laboratory reagent, not a medicine, food or cosmetic.

What purity and identity do you publish for IGF-1 LR3?

≥98% HPLC. CAS 143045-27-6. Sequence Long R3 IGF-1 (83 aa). Mass 9111.5 g·mol⁻¹. Method HPLC.

How fast does a UK order arrive?

Next-day tracked UK delivery is £5 on every order. Discrete laboratory mailer. UK addresses only. Guest checkout — you get a PP- order ID and a tracking number.

Does this vial include the reconstitution kit?

Peptide orders over £75 include USP-grade bacteriostatic water and individually packaged sterile syringes. Under £75 the vials ship without the kit. The kit is a laboratory accessory, not a protocol.

From the bench and the doorstep

IGF-1 LR3 reviews

700 reviews on this listing — mostly five stars, some fours, a handful of threes. The shop is new; the house is not.

4.5

700 reviews

5 star61%
4 star30%
3 star9%

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IGF-1 LR3 1000mcg

£100.00